User guide

210 Advanced User Guide
8 Inlets
To develop a MMI method that uses large volume injection
This topic provides a recommended way to change from a
splitless injection using a split/splitless inlet to a solvent vent
mode injection using a Multimode inlet (MMI). It applies mainly
to large volume injections (LVI) using a Multimode inlet, but the
concepts can apply to general MMI use. This topic does not
consider all items that can impact an analysis, for example the
liner, solvent, analyte boiling points, or polarity. This topic also
assumes knowledge of your data system—when to save a
method, how to start a run, how to set up a single run, etc.
The main advantage of the MMI's solvent vent mode is that you
can inject slowly into the inlet, allowing large amounts of
solvent to evaporate in the liner (not in the split vent line),
Valve
Frit Frit
Valve
EPC Module
Valve
Split Vent Trap
MMI Weldment
FS = Flow Sensor
PS = Pressure Sensor
FS
PS
PS
Split
Carrier Supply
80 PSI
Septum Purge
Column