User guide

44 Multimode Source for 6100 Series Single Quad LC/MS User Guide

3 Reference

Overview

Benefits of a multimode source

Figure 26 Multimode source.

The multimode source is an ion source for LC/MS that can operate as an APCI,

ESI or simultaneous APCI/ESI source. See Figure 26. The source is intended

to operate at normal chromatographic flow rates 50 to 2000 µL /min. It is

capable of fast reversing pos/neg switching. The multimode source can be run

in three different modes of operation (MM-ES, MM-APCI or MM-ES+APCI).

Why use the multimode source?

• A single ion source with a single nebulizer performing MM-ES, MM-APCI, or

MM-ES+APCI

• MM-ES to MM-APCI without source exchange

• Operates in MM-ES only, MM-APCI only, or MM-ES+APCI mixed mode

• Operates at typical HPLC flow rates up to 2 mL/min, even in MM-ES mode

• Multimode source provides higher throughput for data requiring validation

in both MM-ES and MM-APCI

• More universal response