User guide

Multimode Source for 6100 Series Single Quad LC/MS User Guide 21
Basic Operation and Maintenance 1
To bake out the LC/MS
To bake out the LC/MS
You will need to bake out the LC/MS the first time you turn the system on and
any time that the system has been vented.
1 Connect the LC/MS inlet tubing (p/n 0890-1915).
2 Select the Tune view.
3 Select Tune > Manual Tune
4 Display the MS Tune Spray Chamber dialog box.
5 Set the drying gas flow to 7 L/min for MM-ES or 5 L/min for MM-ES+APCI
or MM-APCI.
6 Set the nebulizer pressure to 40 psi.
7 Set the drying gas temperature to 300°C.
8 Set the vaporizer temperature to 250°C. (MM-ES+APCI or MM-APCI only)
9 Set the LC flow to 0.5 mL/min using the solvent mixture appropriate for
your instrument model. Refer to the 6100 Series Installation Guide for
more information.
10 If you are doing performance verification on 6130 or 6140 only, install the
2.1 x 30mm x 3.5 micron B-C18 Rapid Resolution column.
11 Make sure the position of the MS selection valve is set so that the LC flow is
diverted to the spray chamber (select Switch Stream > MSD)
12 Allow the system to bake out for at least 2 hours.
CAUTION
If the system has been exposed to humid conditions during shipping or storage, a
minimum of 4 hours bake out is required to prevent arcing of the quadrupole.