Technical data

28 Multimode Source for 6400 Series Triple Quad LC/MS Set-Up Guide

2 Performance Verification

To set up a method to use the multimode source

1 In the MassHunter software, change the Context to Acquisition.

2 In the MS QQQ tab, set Ion source to MMI (see Figure 22 on page 29).

3 In the Time Segments table, chose an ionization mode from the Ion Mode

list. You may set the ionization mode to one of the following:

• ESI

• APCI

• ESI+APCI

The Ion Mode selection ESI + APCI will specify a method for Simultaneous

ESI and APCI operation.

Note that the Ion Mode selection is only visible if Ion source is set to MMI.

4 In the Source tab, set the desired source conditions. See “Guidelines” in the

Agilent G1978A/B Multimode Source Maintenance Guide for suggested

source conditions for the multimode source for the different ionization

modes.

5 Make any other changes that are necessary for your method.

6 Save the method.