Technical data
Table Of Contents
- Content
- Installation
- Set-Up
- Installation Verification
- Step 1. Auto tune
- Step 2. Set up method names and parameters
- Step 3. Create MMCHECKTOF_EI_POS.m
- Step 4. Create MMCHECKTOF_EI_NEG.m
- Step 5. Create MMCHECKTOF_CI_POS.m
- Step 6. Create MMCHECKTOF_CI_NEG.m
- Step 7. Create MMCHECKTOF_MX_EI POS_CI POS.m
- Step 8. Create MMCHECKTOF_MX_EI NEG_CI NEG.m
- Step 9. Run each of the methods created
- Step 10. Calculate the response of Multimode Demo
- Step 11. Fill out Multimode Report for calculation of peak heights
- Index
22 Multimode Source for 6510 Q-TOF LC/MS Set-Up Guide
2Set-Up
To set up a method to use the multimode source
To set up a method to use the multimode source
1 In the MassHunter software, change the Context to Acquisition.
2 In the MS Q-TOF tab, set Ion source to Multimode (see Figure 19 on
page 23).
3 In the Sources tab, choose an ionization mode from the Ion Modes (Seg)
list. You may set the ionization mode to one of the following:
• ESI
• APCI
• Mixed
The Ion Mode selection Mixed will specify a method for simultaneous ESI
and APCI operation.
Note that the Ionization Modes selection is only visible if Ion source is set
to Multimode.
4 In the Source tab, set the desired source conditions. See “Guidelines” in
the Agilent G1978A/B Multimode Source Maintenance Guide for suggested
source conditions for the multimode source for the different ionization
modes.
5 Make any other changes that are necessary for your method.
6 Save the method.
WARNING
The LC/MS diverter valve is an integral part of the G1978B safety system. The LC
mobile phase flow must always be connected to the diverter valve inlet filter. Never
bypass the diverter valve and connect directly to the nebulizer. If the diverter valve is
used in a manner not specified by Agilent Technologies, the protections provided by
the diverter valve may be impaired and the system may catch fire.