Technical data

Methods with Acquisition Parameters 3
TOF and Q-TOF acquisition parameters
Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System Concepts Guide 85
Varying scan speed based on precursor abundance
You can adjust the number of transients as a function of the
precursor intensity. Varying the scan speed is very useful when
you have a complex sample, such as a protein digest. To use this
feature, you mark the Scan speed varied based on precursor
abundance check box on the Precursor Selection II tab.
When this feature is turned on, the MS/MS acquisition rate is
automatically adjusted based on precursor intensity, thus
spending less time on the more abundant peptides and more
time on the less abundant peptides. This should improve MS/MS
quality and hence database matching.
The variable MS/MS acquisition mode can result in one or more
additional precursors being examined per scan cycle as less
time is spent on more abundant precursors.
See the online Help for information on Abundance Dependent
Accumulation and Purity.
Figure 40 Auto MS/MS mode with Precursor Selection II selected