Technical data

58 Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System Concepts Guide
2 Instrument Preparation
Tuning choices
Set Detector Gain
Set Detector Gain adjusts the PMT voltage to obtain consistent
gain (amplification) of the ion current into electrical current. In
the Extended Dynamic Range (2 GHz) mode, it also adjusts the
preamp offset values and the time delay between gain channels.
This tool is a subset of Initial TOF Tune and Standard Tune.
Table 2 on page 53 shows all of the sources that you can use to
run a Set Detector Gain. On all instrument models, you can
perform a Set Detector Gain with a Dual ESI source.
You set the Instrument Mode to Extended Dynamic Range (2
GHz) in the Instrument State tab before running the Set
Detector Gain algorithm.
Manual Tune
See the online Help for detailed instructions to help you
manually tune the TOF or Q-TOF instrument. Only perform a
manual tune if the Autotune options produce a result that fails.
Order of using Autotune choices
Use the tuning options in the following order:
1 Check Tune for the TOF
If necessary, continue.
2 Quick Tune for the TOF (does not exist for the quadrupole)
If necessary, continue.
3 Standard Tune for the TOF
If necessary, continue.
4 Initial Tune for the TOF
Use the same order for tuning the quadrupole, if necessary.
If an initial Tune cannot complete, contact Agilent Support.