Technical data

Instrument Preparation 2
Tuning choices
Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System Concepts Guide 53
Tuning choices
You can see the tuning choices available to you on the Autotune
tab (Figure 21). Notice that you must tune the quadrupole
separately from the TOF for the Q-TOF instrument. Also,
starting with the B.02.01 release, not all of the tuning choices
are available with all sources.
With the ESI, Dual ESI, Dual AJS ESI, Multimode, APPI and
APCI ion sources, you can run Check Tune, Quick Tune, and
TOF Mass Calibration. You can only run Standard Tune, Set
Detector Gain and Initial Tune (TOF) if one of the supported
sources in Table 2 is installed. The Dual ESI source can run all
tuning choices with all instruments.
Also, the Instrument Mode affects which autotunes are
available to use. If the Instrument Mode is Extended Dynamic
Range (2 GHz) mode, then you can perform any of the
autotunes. If the Instrument Mode is not Extended Dynamic
Range mode, then you can only perform Quick Tune and Check
Tune. You set the Instrument Mode on the Instrument State
tab.
The Mass Range also affects which tunes are supported. You
can run all tunes if the Mass Range is Standard (3200 m/z). If
the Mass Range is Low (1700 m/z), you cannot run an Initial
Tune (TOF), an Initial Quad Tune, a Standard Quad Tune or a
Check Quad Tune. The software automatically switches the
Table 2 Supported Sources for All Autotune
Instrument Model Number Supported Sources for All Autotunes
6220 TOF ESI, Dual ESI
6230/6224 TOF Dual ESI, AJS ESI, Dual AJS ESI
6520 TOF Dual ESI
6530 Q-TOF Dual ESI, AJS ESI, Dual AJS ESI
6540/6538 Q-TOF Dual ESI, Dual AJS ESI
6550 Q-TOF Dual ESI, Dual AJS ESI