Technical data

Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System Concepts Guide 5
Contents
1Overview
How does the TOF and Q-TOF system help you do your job? 10
Help for applications 11
Help for data acquisition 11
Help for data analysis 13
How do different ion sources work? 16
Electrospray ionization (ESI) and Dual ESI 17
Dual Agilent Jet Stream Electrospray Ionization (Dual AJS
ESI) 21
Atmospheric pressure chemical ionization (APCI) 22
Atmospheric pressure photoionization (APPI) 24
Multimode ionization (MMI) 25
HPLC-Chip 27
How does the Agilent TOF and Q-TOF mass spectrometer
work? 28
Innovative Enhancements in the Agilent 6550 iFunnel
Q-TOF 31
Innovative Enhancements in the 6540 and 6538 Q-TOF 33
Innovative Enhancements in the 6530 Q-TOF 35
Agilent Jet Stream Thermal Gradient Technology 36
Front-end ion optics 38
2 Instrument Preparation
LC preparation 46
LC module setup 46
Column equilibration and conditioning 48
TOF and Q-TOF preparation – calibration and tuning 51
TOF mass calibration 51
Tuning choices 53
Tune reports 59