Technical data

36 Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System Concepts Guide
1Overview
Agilent Jet Stream Thermal Gradient Technology
The ions passing through the quadrupole analyzer are then
directed through the collision cell where they are fragmented.
The collision cell is actually a hexapole filled with nitrogen, the
same gas that is used as the drying gas. The collision cell design
has axial acceleration for high speed MS/MS analysis. Fragment
ions formed in the collision cell are then sent to the TOF to
enable a user to isolate and examine product ions with respect
to precursor ions.
Agilent Jet Stream Thermal Gradient Technology
This technology is supported on the Agilent 6530 Quadrupole
Time-of-Flight mass spectrometer, the Agilent 6540 UHD
Accurate-Mass Quadrupole Time-of-Flight mass spectrometer,
the Agilent 6550 iFunnel Quadrupole Time-of-Flight mass
spectrometer and the Agilent 6230 Accurate-Mass
Time-of-Flight mass spectrometer.
Agilent Jet Stream Technology enhances analyte desolvation by
collimating the nebulizer spray and creating a dramatically
“brighter signal.” The addition of a collinear, concentric,
super-heated nitrogen sheath gas (Figure 17) to the inlet
assembly significantly improves ion drying from the
electrospray plume and leads to increased mass spectrometer
signal to noise. The Agilent 6530 Q-TOF gets
attomole-to-low-femtomole sensitivity for superior trace level
analyses.