Technical data

Overview 1
Innovative Enhancements in the 6530 Q-TOF
Agilent 6200 Series TOF and 6500 Series Q-TOF LC/MS System Concepts Guide 35
Innovative Enhancements in the 6530 Q-TOF
Ions are generated using an electrospray ion source where the
analyte is simultaneously ionized and desolvated from the
liquid matrix. The first of three (3) innovative Agilent
enhancements is found in the application of Agilent Jet Stream
Technology (denoted as 1 in Figure 9) which improves
sensitivity via thermal gradient focusing and enhanced
desolvation. This technology is described in detail below
(“Agilent Jet Stream Thermal Gradient Technology” on
page 36).
The desolvated ions then enter the mass spectrometer via an
innovative resistive and highly inert capillary transfer tube
(denoted as 2 in Figure 9) that improves ion transmission and
allows virtually instantaneous polarity switching.
Further increase in ion transmission is obtained by
improvement of the pumping speed in vacuum stage 2, resulting
in better ion capture by the first octopole (denoted as 3 in
Figure 9). The ions next pass through the optics and into the
quadrupole analyzer. The quadrupole analyzer consists of four
parallel hyperbolic rods through which selected ions based on
their mass to charge ratio are filtered.
Figure 16 Fast Bipolar Detector