Datasheet

have the RESET pin set to 4 in BluefruitConfig.h for each sketch before uploading, and that Hardware SPI mode is

selected by checking for

/* ...hardware SPI, using SCK/MOSI/MISO hardware SPI pins and then user selected CS/IRQ/RST */

Adafruit_BluefruitLE_SPI ble(BLUEFRUIT_SPI_CS, BLUEFRUIT_SPI_IRQ, BLUEFRUIT_SPI_RST);