Efficacy of High-Level Disinfection with CIDEX® OPA Solution OPA Solution
ospital-acquired infections (HAIs) pose a serious threat to patient safety, affecting more than 2 million patients every year in the United States and many more worldwide.1 As a result, they have received increasing attention from healthcare professionals, as well as state and federal regulatory agencies, hospital administrators, payors, the media, and patients. A number of campaigns are underway to reduce the incidence of HAIs, focusing on prevention practices and changes in reimbursement.
20°C (12 minutes) and at 25°C (5 minutes).* Because the solution is used around the world and claims vary by country, evaluations also have been done based on other times and temperatures. Testing shows that CIDEX OPA Solution is bactericidal when instruments are processed at 20°C for five minutes. CIDEX® OPA Solution has no offensive odor.
form and achieves a significant reduction of the spore form of C. difficile. (See Figure 1) In particular, there were no surviving C. difficile vegetative cells observed after a 2-minute exposure in 0.3% OPA at 20° C. With the spore form of C. difficile, a 2.4 log10 reduction was demonstrated with 0.3% OPA and at least 4.9 log10 reduction with 0.5% OPA after a five-minute exposure.23 that a 0.5% OPA was rapidly mycobactericidal under both “clean” and “dirty” conditions.
Figure 2. Biocidal Activity of 0.3% CIDEX® OPA Solution. mixture was dried on Petri dishes and recovered as described above. Exposure to 0.5% CIDEX® OPA Solution for 5 minutes at 20°C caused a .4-log reduction in the number of viable virus particles.15 (See Table 3) 10 8 Table 3: Virucidal Test with CIDEX® OPA Solution, 5 Minutes at 20°C (Pass Test= .
References 1. Centers for Disease Control and Prevention. Public health focus: Surveillance, prevention and control of nosocomial infections. Morbidity and Mortality Weekly Report. 1992;41(42):783–787. 2. Joint Commission 2009 National Patient Safety Goals—Hospital 2008. 3. APIC Vision 2012. Washington, D.C.: Association for Professionals in Infection Control and Epidemiology. 4. Mitka M. Public, private insurers refusing to pay hospitals for costs of avoidable errors. JAMA. 2008;299:2495–2496. 5.
